Tesamorelin 10mg

Tesamorelin is a synthetic growth hormone-releasing hormone (GHRH) analog used primarily to reduce excess abdominal fat in people with HIV-related lipodystrophy.

What is Tesamorelin?

Tesamorelin is a medication that mimics the action of growth hormone-releasing hormone (GHRH) naturally produced by the hypothalamus. By stimulating the pituitary gland, it increases the secretion of endogenous growth hormone, which in turn promotes fat metabolism, particularly in visceral (abdominal) fat tissue.

Primary Uses

Tesamorelin is primarily prescribed for adults with HIV-associated lipodystrophy, a condition where patients develop abnormal fat accumulation, especially in the abdominal region, as a side effect of long-term antiretroviral therapy. Clinical studies have shown that Tesamorelin reduces visceral adipose tissue without significantly changing subcutaneous fat or body weight, improving body composition and potentially metabolic health.

Mechanism of Action

Tesamorelin binds to GHRH receptors in the pituitary gland, stimulating the release of growth hormone (GH) into the bloodstream. Elevated GH levels then act on fat tissue to promote lipolysis (breakdown of fat) and reduce the amount of visceral fat in the abdomen. This targeted effect helps address the metabolic and cosmetic challenges associated with HIV lipodystrophy.

Administration and Dosage

• Tesamorelin is administered via subcutaneous injection, typically once daily.

• Treatment is usually ongoing as long as there is benefit and no adverse effects.

• Dosage and duration must be guided by a healthcare provider, and patients require regular monitoring of glucose levels, as growth hormone can influence insulin sensitivity.